Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours ยท Estimated delivery Jul 28 - Aug 2
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Histone H3 (mono methyl K36) Recombinant Rabbit mAb (S-859-505)Product Specification Host Rabbit Antigen Histone H3 (mono methyl K36) Synonyms H3K36me Immunogen Synthetic Peptide Location Nucleus Accession P68431 Clone Number S 859 505 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, ICFCM Reactivity Hu, Ms, Rt Positive Sample HeLa, MCF7, Jurkat, NIH 3T3, Neuro 2a, mouse liver, PC 12, C6 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid
Product Specification
| Host | Rabbit |
| Antigen | Histone H3 (mono methyl K36) |
| Synonyms | H3K36me |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | P68431 |
| Clone Number | S-859-505 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, ICFCM |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | HeLa, MCF7, Jurkat, NIH/3T3, Neuro-2a, mouse liver, PC-12, C6 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 ยฐC as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:2000 | Hu, Ms, Rt |
| IHC-P | 1:5000 | Hu, Ms, Rt |
| ICC | 1:500 | Hu |
| ICFCM | 1:500 | Hu |
Background
Histone H3 (mono methyl K36) refers to a variant of histone H3 where the 36th lysine residue (K36) undergoes monomethylation, a crucial epigenetic regulatory mark. This modification is catalyzed by histone methyltransferases (e.g., SETD2, NSD1) and dynamically regulated by demethylases (e.g., KDM2A). H3K36me1 primarily localizes to gene promoters and enhancer regions, where it associates with transcriptional activation. It plays key roles in maintaining chromatin accessibility, facilitating transcriptional elongation, and promoting DNA damage repair. Studies have linked aberrant H3K36me1 distribution to cancers (e.g., leukemia, glioblastoma) and developmental disorders.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy